POWERbody™
POWERbody™ is a “booster” platform that combines Adagene’s SAFEbody® masking platform with cutting-edge cancer treatment modalities to deliver optimal efficacious dosages to the tumor microenvironment, or TME.
POWERbody™ applies our SAFEbody platform to powerful antibody-based modalities such as creating new bispecific T-cell engagers, antibody-drug conjugates (ADCs), or antibodies that are designed to reach beyond the therapeutic potency of traditional monospecific antibodies. Depending on the modality used, these future products may be referred to as SAFE-CarT®, SAFE-TcrT®, SAFE-ADC®, SAFE-iADC® or SAFEbite®.
POWERbody platforms are all designed to facilitate favorable druggability, manageable CMC attributes, and reduced immunogenicity.